Dr. Kerry Hull - Faculty

Dr. Kerry Hull - Faculty

Dr. Kerry Hull

Full Professor – Dean of Science
Phone: 819-822-9600 ext. 2355
Photo of Dr. Kerry Hull

Dr. Hull is a Full Professor in the Department of Biological Sciences. She teaches courses in Animal/Human Physiology, Human Anatomy, Exercise Physiology, and the History of Biology. She earned her Bachelor’s degree in Biology and her PhD in Endocrinology at University of Alberta, and has also undertaken research projects at universities in Delaware, New Zealand, and the United Kingdom. Her research interests focus on the involvement of hormones in growth and reproduction.  She has recently co-authored an Anatomy and Physiology textbook entitled “Human Form, Human Function” and is also involved in the preparation of pedagogical material, lab manuals and study guides.

Research

Growth hormone stimulates growth by binding receptors, resulting in the formation of a complex that induces a response. It remains unclear if receptors can form complexes without growth hormone. Dr. Hull is investigating that question by examining complex formation by normal receptors and by mutated receptors that cannot bind growth hormone.

The objectives of the project are:

  • To use Fluorescence Resonance Energy Transfer (FRET) to quantify growth hormone receptor dimerization in the endoplasmic reticulum and plasma membrane in the presence and absence of growth hormone;
  • To examine the possibility of growth hormone-induced conformational changes in preformed growth hormone receptor dimers using FRET and photobleaching;
  • To determine the effect of mutations in the chicken growth hormone receptor that inhibit receptor binding or inhibit growth hormone action by an unknown mechanism on growth hormone receptor dimerization.

This analysis is the first to explicitly examine growth hormone receptor dimerization using FRET.

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